When you’re an idiot

Everyone sees it but you.
Author
Published

March 1, 2024

So…

Apparently I’ve sent the same post twice because of inattentiveness. And while I’m assembling (focus on ass) a TES slowly to test, it’s no excuse to stop posting.

A mushroom-shaped toad, my dudes

Goosebumps…what are you?!

  • Performed by piloerector muscles

  • Initially purported to make us hairier to get warmer

  • Also makes us bigger (you wish) to threaten the enemies

  • Is interconnected to brain regions responsible for processing arousal, emotion and motivation

  • One example of the former point is music: it’s filled with unpredictabilities -> sometimes perceived as a low-level threat, activating our FoF (flight-or-flight) response -> piloerector (don’t you like this word, too?)

  • An author of a goosebump study, Michell Clover, mentioned "To your brain, there's no such thing as a pleasant surprise"

  • Activation of a follicular stem cell was found to be necessary to activate goosebumps, at least in mice -> triggering new hair growth -> potential hair loss therapy?

VX-548, a potential new pain enigma

After a successful Phase 3 trial, Vertex’s happy, but let’s delve further into VX-548’s mechanism:

  • It’s an oral and selective NaV1.8 sodium ion channel inhibitor

  • NaV1.8 is specifically transporting thermal and mechanical damage signals -> pain!

  • Wiki claims it’s surprisingly stable concerning depolarization: when other ion channels may be cucked out with electricity, this bad boy can still activate and give you a pain in any part of the body!

More linkies!

Some nice robotics MOOC

WhereCanILive

Cheapest countries

Safest countries

Best countries

Take care <3


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Citation

BibTeX citation:
@online{kogan2024,
  author = {Kogan, Zakhar},
  title = {When You’re an Idiot},
  date = {2024-03-01},
  url = {https://teleogenic.com/posts/240301-bridge/},
  langid = {en}
}
For attribution, please cite this work as:
Kogan, Zakhar. 2024. “When You’re an Idiot.” March 1, 2024. https://teleogenic.com/posts/240301-bridge/.